Which factor is NOT listed as a cause of burning upon injection?

Which factor is NOT listed as a cause of burning upon injection?

• A. Acidic pH of the solution
• B. Injection too fast
• C. Cartridge wiped with alcohol or sterilizing solution
• D. Cold solution

Answer: (D)

Burning upon injection comes from tissue irritation caused by the chemical and how the injection is given. Solutions that contain a vasoconstrictor are kept acidic to preserve the drug, so when they’re injected they irritate the tissues and can feel like burning. Injecting the solution too quickly also irritates nerves by rapidly distending the tissue, which worsens the burning sensation. If the cartridge or stopper has been wiped with alcohol or a sterilizing solution and residual antiseptic remains in the syringe, that irritation can produce burning as well. Cold solution, while it may feel uncomfortable, is not considered a cause of burning in typical practice guidance.

Burning upon injection comes from tissue irritation caused by the chemical and how the injection is given. Solutions that contain a vasoconstrictor are kept acidic to preserve the drug, so when they’re injected they irritate the tissues and can feel like burning. Injecting the solution too quickly also irritates nerves by rapidly distending the tissue, which worsens the burning sensation. If the cartridge or stopper has been wiped with alcohol or a sterilizing solution and residual antiseptic remains in the syringe, that irritation can produce burning as well. Cold solution, while it may feel uncomfortable, is not considered a cause of burning in typical practice guidance.